AUTISM
AND "AUTOIMMUNE" DISORDERS:
THE ROLE OF POLYMORPHISMS, T-REG CELLS, CYTOKINES,
BIOFILMS, VECTOR-BORNE PATHOGENS, AND
THE BLOOD BRAIN BARRIER

Pathogen Load of a formerly healthy 18 yr old female (CW) Post Gardasil - Gardasil is notorious for reactivating dormant pathogens.
a.k.a. GARDASIL SYNDROME
a.k.a. CERVARIX SYNDROME
a.k.a. VACCINE INDUCED AUTISM SYNDROME (VIAS)
a.k.a. VACCINE INDUCED GULF WAR SYNDROME (VIGWS)
Simplified Version v1.46 Copyright© May 8, 2012 - Working Copy; Publication Pending
PHILLIPS OFFIT WAKEFIELD Syndrome documents specific pathways involved in immune system dysregulation, which, when triggered, may result in a cascade of potentially life-threatening events, ranging from Autism and autoimmune disease, to death.
PHILLIPS-OFFIT-WAKEFIELD Syndrome is commonly misdiagnosed as "Conversion Disorder" or "Psychogenic" by poorly trained medical personnel.
SYNOPSIS This older version (1.183) may be freely distributed, if left intact and unedited.
Note: Revealing parts of a government study were presented in early 2012, by the American Association for Cancer during a conference in Chicago. Researchers at the University of South Carolina, in Columbia, studied 326 white and 113 black students. The HPV viruses were found to live 18 - 24 months in black students, but only 12 months average in white students. No significant inflammatory responses have yet been found among races in our study.
A detailed BRIEF, explaining the Pathology of this Syndrome in simple terms that even Paul Offit can understand: Trauma to the immune system can cause inflammation, an immune response. Under certain conditions, the resulting inflammation may fail to self-limit, and cascades of debilitating and/or life-threatening events may follow (Phillips et al, 2010).
Inflammation is typically initiated by one or more of the following four events: 1) Vaccination(s), especially concomitant or closely spaced, such as the Gardasil HPV vaccine; 2) Accidental or deliberate trauma to the body, including concussion or whiplash, which is more dangerous in females; 3) Invasive surgical procedures; 4) Acute or sustained exposure to, or ingestion of (pathogens) mold, fungus, pesticides, or other environmental toxin(s). The risks posed by toxins increases according to the time spent in an air-conditioned environment, due to the retention of toxins that would normally be expelled from the body by sweat, a natural detoxifer.
The cause of the excessive or uncontrolled inflammation is typically due to one or more of three risk factors: 1) genetic defects or variants, including common genetic variants, called polymorphisms (genetic defects that are found in 1% or more of the population), especially those associated with a Glutathione S-Transferase Deficiency, such as a GSTM1 genetic defect, which is found in 59.6% of the population. This common genetic defect causes the liver to be less efficient at filtering out toxins and metals from the body, including the aluminum hydroxide from vaccines, anti-perspirants, and ingested aluminum from baking powder and antacids, 2) body burden, such as active infections, or latent or dormant pathogens such as spirochetes, protozoa, parasites, bacteria, and viruses, especially the arthritis-associated Epstein Barr Virus, and 3) pathogen-hijacked cytokines, which can change the way genes act. An example is Acne Vulgaris, which inhibits Interleukin-10, an anti-inflammatory cytokine (hormone), and prevents it from effectively stopping inflammation throughout the body. The cytokine is actually "genetically hijacked," and turned into "viral interleukin 10."
As an example, in the documented case of an 11 yr old Canadian girl, vaccinated with the Gardasil HPV vaccine, cascades of inflammation, initiated by the vaccine, contributed to/resulted in, infected leukocytes migrating into her joints, which resulted in Diffuse Pigmented Synovitis, an inflammatory condition which infects and corrupts joints. Metals and other toxins may enter the brain and Central Nervous System, when overly sensitized mast cells, typically the result of one or more (concomitant) vaccine adjuvants during vaccination, triggers the release of elevated levels of histamine, which dilates blood vessels (causing fainting, lightheadedness, and low blood pressure), and permeates the Blood Brain Barrier. This was observed by Phillips et al, 2010, who determined that many of the girls who "fainted" shortly after receiving the Gardasil HPV vaccine, appeared to suffer a "toxic shock" type of reaction to a component in the HPV vaccine, and one medical student, who is now a doctor, reported that her blood pressure had plummeted to 50/32, possibly indicating a massive histamine release from mast-cells, possibly triggered by sensitized/overabundant eosinophils (Piliponski et al: Int Arch Allergy Immunol 1999;118:202-203 (DOI: 10.1159/000024067). A significant number of the families stated, during interview, that they had previously been exposed to areas where a mold or fungus existed, and many of these children and young adults had suffered a (serious) reaction at the time of initial exposure. Large amounts of histamine are released during teething, making this a potentially dangerous time to vaccinate an infant or toddler, because of the predictable permeation of the blood brain barrier. Aluminum Hydroxide from vaccines and other sources, has an affinity for attaching to, and degenerating or destroying neurons, especially the motor neurons in the spinal chord (PMID: 19740540), (PMID: 17114826), (PMID: 10335362). If inflammation is not immediately brought under control, additional mast cells may become sensitized and proliferate (producing Mastocytosis-like symptoms), resulting in (increased) allergies, asthma, and food allergies, which may result in additional cascades of inflammation when these newly sensitized mast cells are triggered.
This study also revealed that a significant number of infants, children, and adults, who were ultimately diagnosed with Bartonella, had been bitten by fleas. Family pets, especially ferule (wild) cats, are known reservoirs for Bartonella and Lyme-related infections. These infections may appear dormant after initial exposure, but become activate when the subject's immune system suffers a significant inflammatory event, such as a vaccination. In one docummented case, a neighbor of a man who fed ferule cats, was bitten by fleas from these cats in her own yard. The woman suffered with debilitating and undiagnosed Bartonella, FL1953, and other Lyme co-infections for years.
Recent research indicates that Borrelia burgdorferi, Lyme Disease, is becoming more common, and can remain undiagnosed for years, and may be approaching epidemic proportions (PMID: 16704808), (PMID: 18641487), (PMID: 836338). In 2006, 10,000 cases of Lyme Disease were reported, and 30,000 were reported in 2008. Phillips et al. estimate that less than 1% of the actual cases of Lyme Disease are actually reported, citing the failure of prominent institutions like Children's Hospital of Philadelphia, Johns Hopkins, and others, to diagnose Lyme Patients. Instead, they have been dismissed with "CONVERSOIN DISORDER." Only a rare group of doctors, commonly known as Lyme Literate Medical Doctors (LLMD), have kept their education up-to-date, and are capable of diagnosing and treating Chronic Lyme disease. Due to financial interests, insurance companies, and politics, mainstream medicine wrongfully sells expensive and sometimes inappropriate drugs, in an effort to treat chronic Lyme Disease symptoms, and manage pain. (required reading: http://scientificliving.net/2010/07/the-lyme-epidemic-idsa-caught-with-conflicts-of-interest/). Phillips et al have found that the Gardasil HPV vaccine is notorious for activating/re-activating dormant Lyme Disease and/or Lyme Disease Co-Infections, such as Bartonella, FL1953, Babesia, Mycoplasma, etc., in addition to enteroviruses such as Epstein Barr. Many medical professionals fail to keep up to date with environmental issues that can seriously effect their patients, such as the Giant African snails currently invading South Florida (early 2012), which carry "Lungworm" that can cause meningitis (swelling of the brain). A protozoa called FL1953, is the 'new kid on the block,' and preliminary data suggests that it is very common, and appears to be strongly associated with Multiple Sclerosis. Pathogens such as Epstein Barr Virus and FL1953, formally known as Protomyxoa Rheumatica, may go from dormant to virulent during periods of chronic inflammation. These pathogens "hibernate" in persister cells and biofilms. Like the textbook pathology of 70% of the cases of Viral Encephalitis, as described in the MERCK MANUAL, these and other pathogens, like Lyme Disease and the infections that are commonly found with it, may become virulent and appear years after the initial exposure, and can cause Chronic Fatigue Syndrome, mood swings, joint pain, severe headaches, sensitivity to light and sound, blurred vision, seizures, plus many more symptoms. Inflammation incubates these dormant pathogens, commonly through TH17 inflammatory cytokines. Many doctors often tell the patient that it's all in their head, especially if the patient is a young girl, and dismiss symptoms as "hormone related." Lyme Disease spreads through the body primarily by infected leukocytes, and secondarily, by blood and other body fluids, and may infect other humans through saliva and breast milk (PMID: 9119462), (full study: Am. Journal of Pathology), (Infection and Immunity: Apr. 1997, p. 1273–1285). Human environmental toxin sensitivities to "FDA Approved" chemicals are also proving to be deadly, especially in the immunocompromised. An example of this was the sudden increase in death rates among Cleveland Clinic's dialysis patients, when a Miami area municipality suddenly switched to a bromine water purifying agent. Bromine attaches to iodine receptors, and may further inhibit thyroid function. Common pathogens that hijack cytokines include, but are not limited to: infectious vector-borne bacterium, such as the seizure-causing Bartonella; Borrelia Burgdorferi (Lyme Disease); Babesia, which feeds on the iron in Heme Cells (red blood cells), thus causing "air hunger," and eats the iron out of joint cartilage, leaving iron oxide deposits behind; plus the recently identified FL1953 Protozoan, a.k.a. Protomyxoa Rheumatica, which preliminary data suggests is associated with Multiple Sclerosis and Chronic Fatigue Syndrome (CFS). Cytokines (hormones) that normally control inflammation, such as Interleukin 10, may fail to do their job. Interleukin-10, an anti-inflammatory cytokine that helps keep inflammation in check, may become "viral Interleukin-10 (vIL-10)" when infected by something as common as the Acne Vulgaris bacteria. This means that a person with Acne cannot efficiently limit inflammation and swelling. Deaths resulting from the near epidemic of Babesia and other infectious pathogens from blood transfusions and blood products, including vaccines, is just beginning to be uncovered, pointing to the extent of the contamination of the American blood supply and the drugs made from human tissue and blood products (PMID: 21893613), (PMID: 16507014). Three common initiators of inflammation are: 1) accidental or deliberate physical trauma to the body; 2) invasive medical procedures; and 3) vaccinations. Of these three, vaccinations result in the greatest number of adverse and life-threatening events, and virtually all begin with the inflammation producing vaccine chemical additives called adjuvants. Adjuvants typically force the antibody producing "TH2 immune system" to be "turned on" for unnaturally long periods. The activation of microbial products, such as found in PREVNAR and other vaccines, occurs through the interaction of Toll Like Receptors (TLRs), which results in the signaling of pathways, such as NF kappa-B, which promote the release of pro-inflammatory cytokines. Without advanced immune-response testing, such as a minimum would include C3a and C4a as part of a Wellness Visit, which would cut into the profits of doctors belonging to the 'American Academy of Pediatrics' labor union, the potentially uncontrolled amount of inflammation, initiated by a vaccine, can be potentially life threatening for a small, but growing, subset of the population.

Uncontrolled inflammatory immune response 9 days post Hep B vaccination, just
hours before death.
Note signs of vaccine-induced SJS on infant's face and hands.
Newly published research from 2012 reveals that the Hepatitis B vaccine causes
the inflammation and death (apoptosis) of cell Mitochondria (PMID:
22249285).
The amount of inflammation varies between individual patients receiving vaccines, and may can become potentially more dangerous and life threatening when multiple vaccines are administered concomitantly (given within a short period of time). Each individual's unique immune response is never exactly the same for any two given times, and constantly varies with the unique state of health and varying pathogen load of the patient from hour to hour. For this reason, vaccine manufacturers, such as MERCK PHARMACEUTALS, have quietly excluded people who have allergies, or who have previously received any other vaccine(s) within a four week period. These people are NOT allowed to participate in clinical trials of their vaccines, including the company's own Gardasil HPV Vaccine (MERCK: Gardasil "ClinicalTrials.gov" - see "EXCLUSION CRITERIA" for the "MOTHER-DAUGHTER INITIAVE"). Unfortunately, doctors with financial interests, such as Paul Offit, publicly and wrongfully tell parents and children with allergies that vaccines are safe for them, and in the case of Paul Offit, state that an infant can be given 10,000 vaccines at the same time, while vaccine manufacturer MERCK will exclude a child from their clinical trials if they receive even one additional vaccine. Many misguided pro-vaccine groups dictate the need for "antibodies" to be present for the body to fight a pathogen, while failing to acknowledge, and completely ignoring the existence of Natural Killer (NK) Cells of the innate immune system, the body's first line of defense. NK Cells are pre-programmed to fight viruses, bacteria, vector-borne pathogens, and even cancer. The adjuvant in vaccines, especially aluminum hydroxide, is very efficient at activating the immune system, but the resulting inflammatory hormones, such as Interleukin-18 and Interleukin-1β (one beta), are now increasingly being documented for causing damage to the gut, brain, airways and lungs. Peer reviewed and published literature shows that inflammatory Interleukin-18 and Interleukin-1β (one beta) produce inflammation in the gut (PMID: 17404311) & (PMC1373865), inflammation in the brain (PMID: 11898392) & (PMID: 21184660), and inflammation in the airways and lungs. Interleukin-18 and Interleukin-1β have been documented to be associated with asthma and Chronic Obstructive Pulmonary Disease (COPD) (PMID: 15668323) & (PMID: 10471611). Under most circumstances, the inflammation is self-limiting. In a growing subset of people, this self-limiting does not occur, especially when excessive inflammation is generated from the administration of multiple (concomitant) doses of vaccines. The immune system may then form biofilms in an attempt to isolate foreign pathogens. According to research conducted by Washio and Morikawa of Hokkaido University in Japan, these biofilms can produce vitamin K2 in the form of Menaquinone (MK-7), at concentrations of 0.5 micrograms per milliliter in a 24 hour period. Menaquinone is a clotting co-factor, and can result in blood clots, or exacerbate existing clotting disorders, and may contribute to life-threatening adverse effects, such as SIDS. Mycotoxins from the yeast or fungus medium, used to grow viruses and bacteria for vaccines, may cause a massive histamine release (allergic response) when injected into a sensitized person, especially those people with elevated eosinophils. This may cause a sudden dilation of blood vessels, which may result in syncope (fainting) as blood pressure suddenly plummets [PHILLIPS et al, 2010]. This has resulted in documented BPs as low as 50/32 in one medical student, who "fainted" after returning to class, within minutes of receiving the Gardasil HPV vaccine. Newly published research from 2012 reveals that the Hepatitis B vaccine causes the inflammation and death (apoptosis) of cell Mitochondria (PMID: 22249285). Mitochondria are present in every cell of the body, and compromised mitochondria inhibit the immune system and metabolic functions. Five concomitant vaccines, containing both aluminum and mercury adjuvants (different metals), may result in a synergistic increase in inflammation that is many times greater than the expected 500% (PMID: 731728). The primary Blood Brain Barrier consists of tightly packed endothelial cells in the walls of capillaries in the brain, while Glial cells make up the brain's secondary Blood Brain Barrier, and surround the capillaries. Glial cells are macrophages that outnumber neurons 10 to 1, and help regulate nutrients flowing to the brain by active transport. When Glial cells become inflamed, a proportionate number of oligodendrocytes also become inflamed. Oligodendrocytes are the macrophage cells in the brain that make the myelin sheath that surrounds nerves. Failure of this protective myelin sheath around nerves results in degenerative nerve diseases, such as Multiple Sclerosis (MS). The continued ingestion of metals, including the use of aluminum based anti-perspirants, antacids, or foods containing aluminum, including baked goods using an aluminum baking powder, will now help to sustain inflammation, and some aluminum (al[+3]) may pass through the inflamed and permeated blood brain barrier, and contribute to a further debilitating neurodegenerative cascade of events. GABA supplementation is cautioned in an individual with a blood brain barrier disorder, as it may severely disrupt cognitive functions. To feed inflammation, the body needs additional calcium, magnesium, etc., and may break apart mineral-rich biofilms, which the immune system uses to quarantine pothogens. The pathogens that were formerly encapsulated in antibiotic resistant biofilms, including vector-borne pathogens and co-infections transmitted by mosquitoes, fleas, spiders, ticks, human or animal saliva, etc., are now exposed, and may become virulent, resulting in a further debilitating cascade of inflammatory events. In 2001, a pandemic of Lyme Disease was detected in 90% of the 100 New Jersey horses tested: "Antibody titers to B. burgdorferi were detected in 90 (90%) serum samples by ELISA, with 15 (17%) of the positive horses having reciprocal antibody titers of 10,240 or greater" HAGSTOZ et al, 2001: Bulletin of the New Jersey Academy of Science, Fall 2001, vol. 46, issue 2. In study, all female children who were tested in a group who reported severe adverse reactions to the Gardasil HPV vaccine, and who were typically diagnosed with "Conversion Disorder," actually had NK-CD57 counts ranging between 8 and 51. Further testing revealed that they were infected with varying degrees of Bb, Bartonella, Babesia, FL1953 (Fry Labs: PCR for FL1953), plus other pathogens and Lyme-related co-infections (PHILLIPS et al, 2011). A fully intact Blood Brain Barrier passes Spirochetes, such as Borrelia, commonly referred to as Lyme Disease. Viruses and enteroviruses, such as Epstein Barr Virus (EBV), CMV, XMRV, etc., may also be reactivated. Fast growing Interleukin-17 cytokines, from the recently discovered TH-17 immune response, have now been documented as being capable of acting as incubators for viruses and pathogens, such as Epstein Barr, which may help explain the increase of autoimmune symptoms during flares of inflammation. Attenuated viruses from vaccines may also multiply under these circumstances, as may be evidenced by the 83% increase of antibodies to the strain of measles found in the MMR vaccine in the serum of autistic children. These antibodies are not found in normal children, nor in non-autistic siblings of autistic children (PMID: 12849883). Bartonella henselae, commonly transmitted by mosquitoes, fleas, and other arthropods, may be reactivated, and may infect and inflame the optic nerve and liver, cause endocarditis, result in acute pain in areas of infection, cause streaks and rashes after showers, plus much more, including papules or nodules on the skin, and tumor-like masses, known as Bacillary angiomatosis (BA). Bacillary angiomatosis may also affect the brain, bone, bone marrow, lymph nodes, GI tract, respiratory tract, spleen, and liver. Pathogen-infected leukocytes may now migrate into joints, and in the documented case of an eleven year old Canadian girl, resulted in Diffuse Pigmented Synovitis. Bartonella, FL1953 (Protozoa Rheumatica), Borrelia burgdorferi, and other vector-borne pathogens have been observed in a significant number of the girls suffering adverse effects from the Gardasil HPV vaccine (Phillips et al, 2010). According to recent peer reviewed and published data, the arrogance, ignorance, negligence, and failure of the AMA, AAP, AHA, and many doctors to recognize, acknowledge, diagnose, and treat the epidemic of Lyme Disease, is just now beginning to be addressed (PMID: 20508824), along with associated co-infections, such as Bartonella and Babesia, from infected vector-borne sources and contaminated blood transfusions in the immunocompromised and elderly (CDC: Journal of Emerging Infectious Disease, Volume 18, Number 1—January 2012). Infections, such as Babesia, may last from months to years (PMID: 9664092). The multitude of antibiotics wrongfully prescribed to these patients appears to be contributing to making the growing incidence of Lyme Disease and its co-infections, antibiotic resistant (PMC: 2876246) (PMID: 18447934) (Reuters) (FOX NEWS). Bartonella has recently been found in lice from the homeless in San Francisco (PMC: PMC2727331). Persister cells, a form of antibiotic resistant dormant pathogen(s) (PMID: 20528688), may also be signaled to become virulent, and appear to be more readily reactivated in the presence of metals such as Pb(2+) and Al(3+), and also by metals typically found in mineral supplements such as Co(2+), Ni(2+), Cu(2+), and Zn(2+). Because of peer reviewed and published abstracts, we find that the aluminum hydroxide adjuvant in vaccines, Al(3+), allows biofilms and persister cells to become more accessible to re-infect the human body (PMID: 15946294), which may help explain susceptibility to (rare) chronic infectious diseases, such as Nontuberculous Mycobacteria (NTM), simply by inhaling mist from a shower head while washing (PMID: 1120248), (PMID: 21728159), (PMID: 19824053). The aluminum hydroxide adjuvant in a vaccine may actually increase the risk of infection or disease in a subset of the population harboring biofilms or persister cells (Phillips et al, 2010). Latent or dormant pathogens, in the form or persister cells/biofilms, may be reactivated or made virulent by a vaccination or other immune system trauma. This reactivation may result in a serious or life threatening reaction. Although the technology exists, infants, children, and adults are not tested for any of these potentially life threatening pathogens or deadly inflammatory cytokine responses (deficient T-Regulator cells that can result in uncontrolled inflammation), during "wellness visits," or prior to vaccinations or invasive surgery. It is medical negligence to assume that every child's immune systems responds safely and equally to vaccination(s). While lab animals used for vaccine testing are in *perfect* health and fed *perfect* diets, infants and children are blindly vaccinated, while pediatricians [negligently] fail to acknowledge, test for, or identify the unique and sometimes potentially deadly pathogen loads and polymorphisms of each patient. We hypothesize that human screening, prior to vaccination, would greatly reduce or virtually eliminate vaccine induced autism. Upon detection, immediate treatment of vector-borne pathogens would significantly reduce present and future "autoimmune disease," and reduce the billions of dollars in Federal funding needed to treat these patients and their disabilities. Unfortunately, this would cut deeply into the profits of drug manufacturers and investors like Senator John McCain, Donald Rumsfeld, and others, who rely on the U.S. Population to pay virtually any price for doctors and prescription drugs, in an effort to remain pain-free and in good health. However, when vaccine manufacturers wish to prove the safety of their vaccines, they will often allow only one vaccine to be administered, and exclude people who have ANY allergies, asthma, or immune dysfunction (See MERCK clinical trial: "MOTHER-DAUGHTER INITIAVE" "Exclusion Criteria"). (Note: Doctors should recognize that when a vaccine manufacturer such as MERCK, starts excluding patients from lucrative vaccinations, to obtain good clinical trial results, it has to be based on very serious or possibly deadly inside company information, that is not being disclosed to the general public). Patients with a history of allergies, asthma, Infectious Mononucleosis, or a Vector-Borne Infection such as the FL1953 Protozean, Borrelia (Lyme Disease), Babesia, and Bartonella, present a higher risk for life threatening reactions. The risk becomes even greater if they receive one or more concomitant vaccinations, especially since VEGF from Bartonella and some other infections, can permeate the Blood Brain Barrier, and enter the brain and CNS (Phillips et al, 2010). Pathogens may also enter the brain and CNS through brain stem nerve terminations at the Root Entry Zone (Psychiatry (Edgmont). 2010 January; 7(1): 13–16.; PMCID: PMC2848459). From an autism standpoint, the worst time to vaccinate an infant is while they are teething, because the Blood Brain Barrier that protects the brain and CNS is permeated (opened), due to the elevated histamine produced by teething. Histamine from mast cells in a child with allergies also opens the Blood Brain Barrier. Compared to a 140 pound woman in good health, with no allergies, and a properly functioning Blood Brain Barrier, levels of inflammation-producing vaccine adjuvants are 2,000% higher in a 7 pound infant. An infant girl receives greater neuroprotection because of estrogen, while mercury accumulates in a male child, due to testosterone binding (PMID: 15780490), as can be verified by the higher incidence of autism and related disorders in vaccinated male children. An infant/child/adult who was healthy, may now encounter (flares of) debilitating and sometimes life-threatening symptoms or events. In Phase II (chronic phase), inflammation is typically diminished but sustained, with sometimes intermittent acute flares of symptoms. Pathogen activity may increase. Food sensitivities/allergies may increase as food proteins contact antibody generating immune cells in the lining of an inflamed gut, resulting in new food allergies, which leads to malabsorption, resulting in a new cascade of debilitating events due to decreased nutrients and impaired enzyme production, especially Nrf2 Disruption. Nrf2 is a redox-sensitive transcription factor that upregulates a battery of antioxidative genes and cytoprotective enzymes (PMID: 19023427). Due to elevated LPS stimulated IL-4 and decreased Nrf2, resulting in oxLDL, it is easy to predict CD36 macrophage fusion, which could result in giant cell formation, such as those found in granulomatous infections, such as Sarcoidosis. Serrapeptase has been found to block this formation (J Cell Sci. 2009 February 15; 122(4): 453–459 ). Decreased nutrient absorption results in less Hyaluronic Acid (HA) production, and if Lyme Disease is present, may result in accelerated impairment of connective tissue, ball and socket joints, neuron functioning in the brain and CNS, and a higher risk of vision problems and macular degeneration, due to the attraction of the Lyme Spirochete to these areas of the body that are rich in Hyaluronic Acid. The practitioner must be proficient in using oral Hyaluronic Acid in luring these Spirochetes away from critical body systems and into the gut, where they can be mitigated by the constant administration of low levels of antibiotics, or something as simple as 500-700 milligrams of fresh or freeze dried garlic. If a common (seizure causing) Bartonella bacterial infection has also been reactivated, CD44 may likely be disrupted (upregulated), and the binding properties of Hyaluronan may be impaired, which may result in disruption of neuronal development, cellular regeneration, connective tissue and endothelial cell homeostasis, wound repair, and may contribute to Autism Spectrum Disorder (PHILLIPS et al, 2011). 1,200 genes (mRNA) of endothelial cells were studied after being exposed to a Bartonella infection, and 706 genes and their genetic responses (chemical secretions, etc.) and manifested physical symptoms, were found to be altered by a Bartonella henselae infection (PMID: 16113825), (full transcript: **MUST READING**). While 304 of these genes were found to modify a formerly healthy Innate Immune System, this family of infectious pathogens can and have remained undetected by the majority of 'medical professionals' and institutions, including the prestigious Children's Hospital of Pennsylvania (CHOP), home of Dr. Paul Offit, and Johns Hopkins, home of Neurologist and vaccine developer, Avindra Nath. It is common for these 'medical professionals' to inform their patients that their possible life-threatening conditions are nothing more than a manifestation of their mind, and incompetently and wrongfully diagnose their seriously ill patient with "Conversion Disorder." If multiple infectious pathogens are active (very common), symptoms may appear even more skewed and bizarre. This has been seen in a significant number of patients who experienced adverse effects to the Gardasil HPV vaccine (PHILLIPS et al, 2011). We hypothesize that with the quick onset of Global Warming, the arthropods that spread these pathogens will rapidly increase, and these infections may become even more common and virulent. The addition of, or the regular ingestion of freshly prepared garlic to the diet, may also help reduce Spirochetes and other pathogens. Caution must be used by the practitioner to administer small doses when starting this regimen, to keep the immune response under control, and avoid an uncontrolled systemic inflammatory response in chronically infected individuals as determined by elevated C3a, C4a, elevated LPS stimulated cytokines, or other inflammatory or autoimmune marker, especially low NK-CD57 counts. Additionally, Hyaluronic Acid may stimulate metastasis, so foods that promote angiogenesis are highly suggest in the diet (PMID: 12750291). As you can see through scientific and peer reviewed research, these cascades of debilitating events are predictable, have simple cause and effect mechanisms, can be potently deadly if left untreated, and can be even more deadly in the hands of an uninformed physician. Allergens may stimulate newly sensitized or overly abundant mast cells, and cause them to overproduce histamine (Histadelia), which dilates blood vessels, and can produce MANY other symptoms, including Postural Orthostatic Tachycardia Syndrome (POTS). Because of inflammation, elevated amounts of cortisol are also being released, resulting in short-term memory loss, irritability, fatigue, and much more. The body may become more acidic. As ph decreases, synapse firing is altered, especially in the presence of a Glutathione S-Transferase Deficiency, which can impair mitochondrial activity, due to changes in electrolyte characteristics of body fluids, caused by elevated levels of contaminants and toxins, which affects the electrical charge of the membrane of every cell in the body. A zinc deficiency may contribute to, or exacerbate, a glutathione S-Transferase Deficiency (Journal of Nutrition. 2000;130:38-44). When Glutathione S-Transferase is deficient, CD36 antioxidant functioning/scavanging/binding may be severely impaired, which may lead to toxin disorders from failure to properly dispose of apoptic cells, tissue disorders, and clotting and other pulmonary disorders/events such as excessive LDL and related issues (PMID: 9857015), (PMID: 19023427). Typical inflammatory markers may appear somewhat lab-normal on a Comprehensive Cytokine Panel, except for LPS stimulated cytokines, which may appear 1/4th lab normal, but cytokine base counts will usually appear somewhat normal. Multiple vector borne pathogens have been observed in these in the 2010-2011 study of girls severely affected by the Gardasil HPV vaccine. Bartonella, HHV6, and several others, are suspect if seizures are present. FL1953 is suspect if connective tissue disorders, joint pain, air hunger, or fatigue are present, with or without a positive Western Blot, especially when family pets or livestock are present. Families with a history of Epstein Barr, Mononucleosis, arthritis, asthma, allergies, or a Glutathione S-Transferase Deficiency (GSTM1, GSTP1, GSTT1, etc. polymorphism) are at greatest risk. Through extended interviews with patients, a high arch on the foot, as seen in Charcot Marie Tooth Disease, is being observed in a significant number of affected patients (Phillips et al, 2010), and appears to be an additional risk factor. After the patient is placed on a low-fat, restricted carbohydrate diet, the administration of Low Dose Naltrexone has proven helpful, if started at a safer level of 0.5 milligrams if good liver and kidney function is observed. In cases where inhibited liver or kidney function present, the initial dose must be further reduced to 0.1 milligrams per day in order to reduce/eliminate potential headache or possible thoughts of suicide. (Phillips et al, 2010). If LDN is started at 0.1 milligrams, it should be increased by 50% each two week period, until a 3.0 to 3.5 milligram per day maintenance dose is achieved (PMID: 20965606). If LDN is started at 0.5 milligrams for a patient with AST & ALT within normal range, the dosage may be increased to 1.0 milligram after two weeks, and increased by 1.0 milligrams each week if no adverse effects are observed, until a maintenance dose of 3.0 to 3.5 milligrams per day is achieved. Naltrexone is normally administered at 3.2 milligrams per 100 pounds of body weight, with 3.0 to 3.5 milligrams being optimal for most teens and pre-teens, and should never exceed 4.0 to 4.5 milligrams per day. Low Dose Naltrexone cleared acne within one month on an 18 yr old fem patient, and allowed her to return to dancing. Low Dose Naltrexone has been found to help reduce glial cell inflammation in the brain, which helps restore a permeated blood brain barrier, and return the immune system to homeostasis in cases where an overproduction of T-lymphocytes has resulted in the immune system attacking self (autoimmune disease). Low Dose Naltrexone appears to have the greatest affect on patients with chemical and food sensitivities, typically the result of vaccination-induced inflammation, and helps normalize elevated mast-cell sensitivity [PHILLIPS et al, 2010].
HYPOTHESIS:
We hypothesize that most, if not all, sudden onset autoimmune disease is attributable to pathogens that proliferate under conditions of sustained inflammation. Because the female immune system is more sensitive than its male counterpart prior to menopause, the resulting increased inflammatory immune response would put them at higher risk for what is currently presented as an "autoimmune disease." An autoimmune disease may be looked upon as a doctor who failed to follow through on his diagnosis, by going far enough to find the CAUSE of the inflammation. Although we recognize that a doctor's time is valuable, and insurance companies don't want to pay for this extra step, we believe that the real cause for this MEDICAL NEGLIGENCE lies with the huge profits of the medical community and pharmaceutical companies, who are making huge profits by MAINTAINING and TREATING symptoms such as Chronic Fatigue, but not curing the patient.
PHILLIPS et al, 2012
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Typical Patient Complaints: 1) Fatigue; 2) Memory Loss (short term); 3) Inability to Concentrate (a former "A" student may regress to a "C"; 4) Insomnia (elevated cortisol may inhibit melatonin production by pineal gland); 5) Irritability (difficulty controlling temper); 6) New Food Allergies and/or Environment Sensitivities (symptoms similar to Mastocytosis); 7) Nausea; 8) Photophobia (fixed or dilated pupils in severe cases; 9) Noise Intolerance; 10) Head Pressure/ Migraine (pain similar to carbon monoxide poisoning, [which may account for HEAD BANGING in younger children]); 11) Lightheadedness (with or without Postural Orthostatic Tachycardia Syndrome [POTS]); 12) Depression, sometimes with thoughts of suicide; 13) Seizures (when Bartonella, HHV-6, etc. is acquired or reactivated); 14) Pain in legs/extremities; 15) Tingling in legs/extremities; 16) Involuntary muscle spasms; 17) Loss of time (TIA); 18) Intermittent or sustained pain in joints (Diffuse Pigmented Synovitis has been observed), abdominal cavity (splenomegaly), chest (gall bladder removed in a significant number of children); extremities; 19) ovarian cysts; 20) Blurred vision or temporary loss of vision in rare cases; 21) "Flashes" of light or color(s), even in a darkened room. (one 11 yr old Canadian girl told her mother she "saw angels."); 22) Immune Systems may become "TH1 DOMINANANT" 23) Impaired coordination; 24) Impaired balance; 25) Impaired visual or auditory processing.
Clinical Lab Presentation:
Note: Because typical labs may appear fairly normal, extended testing methods
must be employed to avoid a wrongful diagnosis of Conversion Disorder):
1) Vitamin D, 1,25(OH)2D and intracellular magnesium will plummet, with
extracellular serum magnesium levels typically within the lower 15% of normal. Active Vitamin
D plummets due to CYP450 deficiencies and its high demand in cell apoptosis of pathogen-infected cells.
Apoptosis is triggered by the C3a and C4a compliment, and both C3a and C4a will
typically be elevated. Magnesium is depleted during these periods of
oxidative stress. 2) During the acute phase, a Comprehensive
Cytokine Panel may reveal extreme deficiencies of Interleukin 4 and Interleukin
6. An Interleukin 4 deficiency will increase the
production of TH1 immune cells, and makes the TH1 immune system DOMINANT.
Depleted Interleukin 6 will skew IFN-gamma base counts, while
inhibiting the proliferation and activation of T-Cells and B-Cells, thus compromising the body's ability to fight infection
{{{ BOOKMARK: need more data: How extensive is the
rs10741657 'G' variant of the CYP2R1 polymorphism in this group
(PMID: 17607662) ??
does IL-6 deficit contribute/ inhibit secretion &
conversion to active "vitamin D, 1,25(OH)2D" by the liver and kidney through
CYP-450??? Does this IL-6 cytokine deficit affect competitive protein
binding assays (CPBA) for 25(OH)D [1]
and 1,25-dihydroxyvitamin D [2]
???? Need info on CYP2R1 [4,5].
(PMID:
PMC1892844) }}}, or produce antibodies. While
overproduction of IL-4 is associated with allergies, the chemical sensitivities
seen in these Interleukin-4 deficient patients is due to overly sensitized or overly
abundant mast-cells. We hypothesize that although Interleukin-6 is
typically deficient, Interleunin-6 production may have initially surged, resulting in
a temporary overproduction of PGE2, which may account for the significant
numbers of reported spontaneous abortions following vaccination. Depletion of
Interleukin 6 accounts for the bouts of erratic body temperatures.
Dysfunctional Pattern Recognition Receptors (PRRs),
including Toll-like receptors (TLRs),
may now signal debilitating cascades of inflammatory cytokine
production. During the chronic Phase, Lipopolysaccharide (LPS) stimulated
cytokine counts may appear far BELOW GATE, but base counts may typically appear
lab-normal. 3) NK-CD57 counts may plummet, and NK-CD57 counts as low as 8
(15yr old female), 15 (17yr fem), and 41 (18yr fem who was also POS for
Bartonella and FL1953) have been recorded in patients with seizures. Patients without seizures have had NK-CD57 counts as low as 22 (15yr fem).
Chronic, undiagnosed Vector-Borne Infections are common among these patients.
4) "PCR for FL1953" (Fry Labs) may reveal the presence of the FL1953
Protozoan on PANEL A, while slides from the FRY LABS "PCR for FL1953 - PANEL B"
may show the presence of spirochetes, Bartonella, etc. 5) C3a and C4a
should be elevated, and testing can be used for a baseline and to track
recovery. It is imperative to use Jewish National Hospital (Denver) for
testing. The IDC-9 diagnostic code is 279.3 (immune dysregulation),
LabCorp #840702 for C3a, and #857334 for C4a. "ACCESSIONING: C3a &
C4a MUST BE ROUTED TO NATIONAL JEWISH" should be written boldly on the LabCorp
requisition slip. Elevated C3a, among other things, is a marker for
autoimmunity, while elevated C4a is indicative of vasculitis, chronic Lyme
(without severe cognitive deficiencies), and much more.

FL1953 PROTOZOAN together with a BARTNELLA co-infection in an 18 yr old patient (CW) with active Borrelia Bands 31, 34, and 41
Typical Patient History: 1)
The majority of these children have a history of walking, hiking, or camping in
areas occupied by biting insects, or exposure to places that were rarely
occupied by humans, including basement crawl-spaces or buildings that were
unoccupied for long periods. Infants and toddlers will typically have been
allowed to play on surfaces or areas that were also occupied by pets who have
had fleas or ticks in the past, or in outdoor areas that were occupied by
wildlife or biting insects; 2) Many of the more severely
affected patients have been seen by 30
to 50 doctors, including specialists at leading
diagnostic facilities/hospitals. 3) Parents/ grandparents will typically have a
history of allergies, asthma, and/or arthritis/Epstein Barr. A history of
"Mononucleosis" or "Glandular Disease" has been found to be a 100% predictor for severe
adverse effects from immune system trauma, such as the Gardasil HPV vaccine.
4) Patients whose family
history includes a very high arch on their foot, as seen in Charcot-Marie-Tooth
Disease, also have been found to be at higher risk for adverse effects. 5) Patients
exposed to pulmonary infections prior to vaccination are at higher risk.
6) Patients exposed to mold are at higher risk. 7) Patients exposed to the
saliva of a cat, dog, or family pet, -or- those receiving a scratch from a cat,
dog, or family pet are at higher risk. 8) Those receiving a bite from an
arthropod (spider, flea, mosquito, gnat, tic, biting fly, etc.) are at greater
risk, especially if a rash that looks like a bulls-eye suddenly develops. 9)
Patients exposed to environments inside old buildings. One girl worked as
a tour-guide in a hundred year old Pennsylvania cloister that was normally kept
closed, while another girl became quite ill after crawling through a basement
crawl space full of spiders, mold, and mouse droppings. Still another
pre-teen came downstairs into a basement that her mother was sweeping. The newly
purchased house that had been abandon for two years. The girl became
violently ill after she walked through a cloud of "dust" that contained animal
feces from cats and dogs, plus droppings from vermin. Many other girls
report hiking or walking in wooded or secluded areas, or being exposed to the
Coccidioides fungus in the dessert Southwest of the United States.
Further Notes: Significant Bartonella infections have been found in this group among patients presenting with seizures. The Methylation Cycle may typically be disrupted. NF-KAPPA-B inflammatory regulators, which are iron dependant, may also be disrupted, which may result in a female patient having debilitating flares of SLE/ME/Lupus-like symptoms during menses, especially if an iron-consuming Babesia infection is also present. The presence of Babesia may also be marked by sporadic bouts of "air hunger" in affected patients. Cortisol-related disorders are common. Thyroid disorders, such as Hashimoto's, may result if no intervention is performed, along with the body temperature running typically between 3/4 to 1 degree below normal. One or both pupils may be fixed or dilated during flares of symptoms. While heart rate may appear low. Tachycardia may commonly present upon rising from a reclining or sitting position, and a Dx of Postural Orthostatic Tachycardia Syndrome (POTS) may sometimes apply, but the underlying cause is the over-release of histamine from overly abundant and sensitized mast cells and/or eosinophils. A low histamine diet may also be suggested by the health care professional, along with a low fat, low carbohydrate diet. Treatment should be left to an experienced practitioner. Vitamin D may not be converted to its 1.25 active form from 25(OH)D3, due to a CYP450 Pathway impairment, and may become seriously depleted if the CYP2R1mRNA "G" genetic variant of rs10741657 is also present in the patient (PMID: 17607662).
CAUTION: The health care professional must be aware of a probable Cytochrome P-450 Pathway metabolic dysfunction, resulting in the patient being unable to metabolize certain prescription drugs which rely on the CYP-450 pathway for their metabolism. This presents a two-fold danger: 1) certain prescription drugs may be rendered useless, and 2) it presents a danger of a toxic accumulation of that drug in the body.
EXTREME CAUTION: Some prescription drugs that break biofilms, such as TINDAMAX, should be used with extreme caution, as these can provoke a life threatening immune response, due to their ability to break apart pathogen-loaded biofilms. Once the protective biofilm layer has been breached, formerly inactive pathogens may be free to attack the body in critically large quantities.

BIOFILM in an 18 yr old female patient (CW) presenting with a clotting disorder, seizures, symptoms of Postural Orthostatic Tachycardia syndrome, muscle pain, muscle twitching, forgetfulness, irritability, nausea, difficulty breathing, and more.
The patient's doctor, Dr. Laura Helen Fisher M.D., an "IMMUNOLOGY SPECIALIST" at the 'Allergy and Asthma Center' in Lancaster Pennsylvania, REFUSED the mother's request to test her daughter for FL1953 and other vector-borne pathogens. Instead, Dr. Laura H. Fisher told the mother that the daughter's condition was "all in her head," and suggested that the seriously ill girl go see a psychiatrist, instead of starting diagnostics and treatment that would save her life. Dr. Laura H. Fisher M.D. serves as a shining example of why doctors should continue to be tested on a yearly basis, in order to keep their license.
This is not an isolated case. Another young girl, Megan Fisher, of Dublin Georgia, has been misdiagnosed for years. Her primary care physician did administer the requested NK-CD57 test, which returned a NK-CD57 count of 8 (this is NOT a typo). The doctor apparently did not know the implication of such a critically low count in a 16 yr old girl. The test results were given to Megan as she lay in her hospital bed on Tuesday, two days after she was admitted for seizures, and 4 days after having blood drawn for the LabCorp NK-CD57 test in her doctor's office, the previous Friday. Although her tests revealed a rather serious immune disorder, the Laurens County (Georgia) Hospitals and the County Health Department appear to have failed to provide proper health care for this young American citizen.
In yet another disturbing situation, involving Johns Hopkins Neurologist, Dr. Avindra Nath M.D., Brittney F., a young girl in his care, was dismissed without treatment after exhibiting severe chronic Borrelia symptoms (with co-infections). Brittney reported that she had received MERCK's HPV vaccine, Gardasil. It shoul be noted that Dr. Avindra Nath is involved with vaccine development, and further, Johns Hopkins recently received a $1,500,000.00 grant from MERCK, maker of the reportedly contaminated Gardasil HPV vaccine. This appears to be a rather blatant conflict of interest.
NOTE ON PANICK ATTACKS: Lyme & Bartonella typically cause muscle twitching, fatigue, rashes that come and go, and sometimes joint pain. When Babesia is present, the patient may feel that he/she cannot take in enough oxygen. This Babesia infection symptom is commonly mistaken for a panic attack, or diagnosed as "CONVERSION DISORDER," or dismissed as a 'psychotic episode,' when it is actually pathological in nature.
NOTE ON FL1953: Preliminary information indicates that the FL1953 may occur as commonly as Epstein Barr Virus, and has at least two variants that respond differently to treatment.
Contributing Factors: The majority of these children have a history of walking, hiking, or camping in areas occupied by biting insects, or exposure to places that were rarely occupied by humans, including basement crawl-spaces or buildings that were unoccupied for long periods. Damp and dark central air conditioning evaporator coils inside furnaces or window a/c units breed mold spores, staph, and other pathogens, but are virtually never cleaned, leaving billions of spores to be re-distributed throughout furnace air ducts and living quarters during hot summer months, and the dry winter heating season. Virtually all had a family history of allergies and/or asthma. Many had a family history of Arthritis, EBV (Mononucleosis was found to be a 100% predictor of an adverse event), and a high foot arch family history, as seen in Charcot Marie Tooth Disease. A GSTM1 genetic Polymorphism was found in those who were tested. Only after they became ill, the Cytochrome P-450 Pathway appeared to be inhibited, thus moderate intake of fats or carbohydrates may produce nausea or flares of symptoms. Ingestion of products containing aluminum hydroxide, such as antacids, baking powder, or even the use of aluminum containing antiperspirants may exacerbate symptoms, and further decrease enzyme production in severely affected patients. The continued use of NSAIDS may further inhibit the immune system, and NSAIDS containing acetaminophen will further reduce/inhibit glutathione production. Citric Acid ingestion may trigger additional flares of debilitating symptoms in a sub-set of severely affected patients infected with Borrelia.
-----------------------------------
Synopsis: Trauma to the immune system,
including vaccination, can initiate a systemic inflammatory condition that may
fail to self-limit, and become more aggressive in individuals with a Glutathione
S-Transferase (GST) deficiency and/or an impaired Cytochrome P450 pathway (CYP)
(Phillips et al, 2010). Acute inflammation may reactivate dormant pathogens, such as EBV,
CMV, HHV6, XMRV,
picornaviruses, etc., and cause a cascade of debilitating disorders, especially when vector
borne pathogens, such as FL1953 (Protomyxoa Rheumatica), are present.
People who suffer multiple or repetitive insect bites, or a single bite
from a tick, are at greater risk. Protomyxoa
Rheumatica (destroys heme cells), Bartonella (seizures), and Babesia (parasite
that loves iron, leaves oxidized iron deposits in joints, and causes "air hunger"),
may enhance the activity of other
infections. Because of increased airway and lung mucus, patients living in
arid climates, or in coastal salt-water areas, may experience lighter symptoms,
compared to those living in inland areas with higher humidity. In many
individuals, oxygen levels may appear normal, but will decrease to below 85%
with light to moderate exercise in severe cases. Decreased exhaled NO
levels may be used to monitor an underlying pulmonary inflammatory condition. During the second phase, inflammation may decrease, and CBC tests
may appear somewhat lab-normal. New food allergies may result when
proteins from favorite foods contact antibody producing immune cells in an
inflamed gut lining, resulting in newly sensitized mast cells releasing
increased amounts of histamine when those foods are later eaten. This
causes new and additional inflammation, which further elevates cortisol that
destroys short term memory neurons in the hippocampus of the brain, and inhibits
the pineal gland from producing the melatonin that is necessary for sleep.
Malabsorption, caused by the inflamed gut, results in
Mitochondrial insufficiency, causing an additional cascade of debilitating
events. The multiple reactivated pathogens may present with multiple complex
symptoms, called "viral interference," making it difficult to diagnose any
single disorder. The patient may go undiagnosed for years, and may present with
symptoms of CFS, forgetfulness, ADD, ADHD, irritability, headache, nausea, joint
pain, photophobia, Mastocytosis, adrenal insufficiency, Gastroenteritis,
Colitis, Connective Tissue Disorders, flares of Lupus-like symptoms, and sometimes idiopathic seizures. These
individuals may have an intolerance to foods with a high fat content,
foods that contain wheat, and foods that contain citric acid. In severe cases,
decreasing barometric pressure, caused by approaching storm fronts, will result
in a flare of symptoms. The patient continues to plateau or decline until 1) cortisol
and histamine producing foods and airborne irritants are removed, 2)
pathogens are identified and brought under control, 3) body burden is mitigated,
4) nutrient absorption is restored, and 5) cycles (ie: methylation) are
normalized or compensated for. ABSTRACT: The PHILLIPS-OFFIT-WAKEFIELD SYNDROME
is a condition in which inflammation moves from physiologic to pathologic,
resulting in a cascade of symptoms of various degrees of Developmental Disorders
and possible seizures in infants and toddlers, and cognitive impairment,
CFS, with flares of Lupus/SLE, Urticaria, Mastocytosis, Schizophrenia, and possible
seizures in older children and adults. Please be aware that these multiple
pathogens skew symptoms (viral interference), making it difficult to diagnose a specific disorder. Self-sustained and sometimes uncontrolled inflammation may be due to
the failure of T-Reg cells such as STAT3, which may cause
Hyper IgE Syndrome;
(RAD51 enhanced) BRACA2 gene, which inhibits human p53 (p53 may also be
inhibited by Stat3, Bartonella, Protomyxoa Rheumatica* (PR) [formerly called FL1953],
etc.); dysfunctional Interleukin 10; SEPS1; or other genetic or environmentally
induced variant or variable. Inflammation is commonly initiated by an acute immune response
to a vaccine adjuvant, typically aluminum hydroxide
(PMID: 17404311), and may become
more aggressive with close-spaced, concomitant, or repetitive vaccination(s),
which cause hyperactivity in T-Cells and B-cells. If an infant is teething, the
body produces elevated levels of histamine that open the Blood Brain Barrier,
which may allow pathogens and vaccine components, such as the highly
inflammatory Aluminum Hydroxide adjuvant in a vaccine, to enter the brain, and
compromise the Central Nervous System (CNS). Aluminum Hydroxide also has
high affinity (attraction) to motor neurons in the spinal cord
(PMID: 17114826),
(PMID: 19740540)..
Interleukin-18 and Interleukin-1β
are triggered by aluminum hydroxide to
produce inflammation in the gut
(PMID: 17404311),
(PMC1373865),
inflammation in the brain
(PMID: 11898392),
(PMID: 21184660), and in airways, where both Interleukin-18 and
Interleukin-1β have
been proven to be associated with asthma and Chronic Obstructive Pulmonary
Disease (COPD) (PMID:
15668323), (PMID:
10471611).
Published research from 2012 reveals that the Hepatitis B
vaccine causes the death of cell Mitochondria
(PMID: 22249285). A significant number of patients recall exposure to places
where a mold or fungus was present, such as a classroom or building where mold
was found, possibly resulting in their immune system becoming dangerously pre-sensitized to vaccines that use a yeast/fungus
medium to grow
viruses, such as the Gardasil HPV vaccine. Subsequent flares of inflammation and
new autoimmune-like symptoms may be triggered by newly acquired food allergies
from food proteins coming into contact with antibody-producing immune cells in
the lining of an inflamed gut. These immune cells may produce antibodies to
favorite foods, causing new food allergies. Histamine-producing mast cells may
become highly sensitized and more abundant, limiting food choices, especially
foods containing histamine-stimulating citric acid. Malabsorption and enzyme
deficiencies may become common, and result in a further cascade of debilitating
and/or life-threatening conditions and events. Dormant viruses, retroviruses,
and enteroviruses, such as Protomyxoa Rheumatica (a protozoan common to North
America, in the Malaria family, formerly called FL1953), XMRV, EBV, HHV6, and vector borne pathogens
such as Borrelia,
may be reactivated during periods of inflammation. (Vaccination against HPV with
Gardasil®, and vaccination against Lyme (Borrelia) with Lymerix®, are
unfortunately proving to be a new source of neurological disorders and adverse
effects, due to the Recombinant Outer Surface Protein (OSP)
(PMID: 21673416).
These pathogens may be incubated and thrive within pro-inflammatory cytokines,
such as Interleukin 17, resulting in obligate intracellular bacteria, such as
Mycoplasma Pneumonia and Chlamydia Pneumonia, Babesia, (the seizure causing)
Bartonella, which may also attack heme cells (discovered 2 decades ago - 24
strains have now been identified), and Protomyxoa Rheumatica, which feeds on
lipids in the blood, and has an affinity for the arginine found in wheat, also
causes coagulation disorders and biofilm growth, and is quickly spreading across
North America. These reactivated pathogens may enhance the activity of currently
active infections. Bartonella is the only genus that infects human
erythrocytes and elevates monocyte-macrophage chemoattractant protein-1 (MCP-1),
which is produced upon infection of endothelial cells with Bartonella henselae.
Bartonella triggers pathological angiogenesis in the vascular bed, due to
mitogenic levels of vascular endothelial growth factor (VEGF) that are able to
cause endothelial cell proliferation. The elevated level of MCP-1 is sufficient
to result in the migration of macrophages to the infected endothelial cells. The
Bartonella bacteria stimulates the growth of its host cells, and may actually
attract pro-inflammatory Interleukin 21 cytokines to epithelial cells in the gut
(PMID:
PMC2915423),
(PMID:
17241869), which may lead to gastroenteritis, IBS, Chron's, and sets the
stage for rarer disorders such as
Disseminated
Intravascular Coagulation (DIC). Bartonella (and possibly other pathogens), attract pro-inflammatory
cytokines to a site, and use these fast growing cells as incubators, especially
during flares of acute inflammation
(Phillips et al, 2010). Pathogen-infected leukocytes may now penetrate and infect joints,
and may result in disorders ranging from arthritis, to rare disorders, such as Pigmented
Villonodular Synovitis, or Ankylosing spondylitis. Elevated and/or waves of
histamine from sensitized or overly abundant mast cells may cause syncope and
lowered blood pressure, due to vascular dilation. Histamine permeates the Blood
Brain Barrier, allowing pathogen access to the brain and CNS. Elevated cortisol
can inhibit and/or kill neurons in the hippocampus, resulting in short-term
memory loss and poor concentration, but fatigue, GI distress, head pressure,
migraines, joint pain, seizures, photophobia, lightheadedness (check for POTS),
insomnia, and mood swings are the most common complaints. Elevated cortisol can
disrupt the pineal gland, inhibit melatonin production, and result in insomnia
and decreased neuroprotection.
The diagnostician must ensure that his patient is
not among the 25% of the population who has an undiagnosed congenital heart
defect known as ATRIAL SEPTAL DEFECT (ASD). The syndrome described in this
abstract may exacerbate ASD, which may contribute/result in cascade of pulmonary
related events, such as difficulty breathing (dyspnea), migraines, pulmonary
infections, and blood pressure disorders.
A Glutathione S-Transferase (GST) deficiency has
been observed in a significant number of these patients, typically due to a
GSTM1, GSTP1, or other GST polymorphism. Other genetic variants that cause
enzyme deficiencies, have been observed in these patients, and may appear and be
exacerbated during this time. Genetic variants such as CYP1A1, CYP1B1, and
CYP2C9, have been observed in the Cytochrome P450 Pathway. These genetic
variants form a bottleneck for the metabolism of nutrients and medications.
After the initial eruption of symptoms in which ANA, TNF-a, SED rate, and other
inflammatory markers may test high, the inflammation becomes attenuated,
possibly due to pathogen “hijacked cytokines” (ie: Interleukin 17 is converted
to viral Interleukin 17 (vIL-17), which may slow the inflammation process and/or
inhibit apoptosis. Slightly lowered body temperature may be observed, possibly due
in part to the
leaching of Bromine and other halides from the surge in cell apoptosis due to
inflammation. Bromine, Fluorine, and Chlorine now compete for iodine receptors and
thyroid related functions, and body temperature regulation may (briefly) become
unstable. During this chronic second phase, in addition to
developing new food allergies and symptoms, a Cytochrome P-450 pathway
deficiency may cause additional flares of debilitating symptoms when fats and
sugars are ingested. Medications metabolized through the Cytochrome P450
pathway may fail, and accumulate to toxic levels in the blood. Typical CBC lab
tests may appear lab-normal, but an “NK-CD57” test (Natural Killer Cell, Marker
57) may display a very low count, indicative of viral activity from HPV viruses
and/or opportunistic or formerly dormant pathogens.
NK-CD57 test counts from four females were 51, 22,
15, and 8. The NK-CD57 test may then be administered at 6 month
intervals to gauge the progress of the patient’s recovery. The girl with
the NK-CD57 count of 51 subsequently tested positive for Protomyxoa Rheumatica,
while the others remain untested. A “COMPREHENSIVE
CYTOKINE PANEL” may reveal that, while cytokine base counts are somewhat normal,
Lipopolysaccharide (LPS) Stimulated IL-17 and other pro-inflammatory cytokines
may test far below acceptable lab limits, thus confirming an underlying and
continuing inflammatory condition. FRY LABS is currently the only lab that
is capable of testing for Protomyxoa Rheumatica (FL1953 Protozoa), and it is
suggested to use "PCR for FL1953, with Advanced Stain,
Panels A and B" (skip the NK-CD57 Panel if you use this test).
Protomyxoa Rheumatica, is widespread and is usually overcome by a healthy immune
system, but presents with symptoms similar to Malaria when reactivated from a
dormant state. Indications of a DOMINANT TH1 immune
system may also surface, making certain dietary choices potentially
life-threatening. Intestinal disorders, including gastroenteritis, are not
uncommon, and gastroparesis has also been diagnosed, which appears to confirm
that intestinal and other problems may become exacerbated without dietary and
drug intervention, such as Low Dose Naltrexone (LDN). LDN affects membrane of
fast-growing cells. To prevent severe immune reactions in patients already
suffering with acute allergies and/or chemical sensitivities, LDN *MUST* be started VERY gradually: 0.5 Milligram for the
first two weeks, then doubling the dose each following week, until a maintenance
dose of approximately 3.5 milligrams per 100 pounds of body weight is reached,
but in no case should the daily dose ever exceed 4.5 milligrams. Increasing the dose
beyond 4.5 milligrams has been found to decrease its effectiveness, and often a
dose of 3.0 milligrams two hours before bed has been found to be very effective.
The object is to temporarily stop the body from producing Opiod Growth Factor
(OGF) and the production of Opiod Growth Factor receptors (rOGF), and fool the
body into producing increased amounts of OGF and also increase the quantity of
OGF receptors on each cell back up to normal amounts. OGF and rOGF are
decreased when certain pathogens hijack the production mechanism in the host, in
an effort to compromise the immune system. Concentrated whey protein has been
administered to decrease gut permeability with positive results
(PMID: 22038507), with
the additional benefit that it also increased glutathione levels. Risk Factors include, but are not limited to: Families with a history of autoimmune disease Families with a history of allergies or asthma Families living in areas with an abundant mosquito, flea,
or tick population Families with a high arch on their foot, with or without a
diagnosis of Charcot Marie Tooth Disease
(CMT) Families with a history of Mononucleosis (Glandular Fever) among
any of its members *Protomyxoa Rheumatica is a vector borne protozoan similar to
Malaria, typically transmitted to humans by fleas and mosquitoes. Protomyxoa
Rheumatica is normally encapsulated by a biofilm.
The safer POWDERMED (PMED®)
vaccination method, that used 1/1000th of the material used by the current
intramuscular method, disappeared in 2008 after POWDERMED was purchased by
pharmaceutical giant, PFIZER. Because the POWDERMED vaccination method caused virtually no inflammation,
it could potentially drastically decreased autism rates, which might have
resulted in massive lawsuits against doctors, hospitals, pharmaceutical
companies, and entities such as governments and school districts, who had
mandated vaccines.
Ancient Greeks typically woman in pain with "HYSTERIA." According to Dr.
Kathy Maglioto, Women and you girls are 22 times more
likely to be misdiagnosed when complaining about pain during a visit to a
doctor. Similar to the ancient Greeks, today's doctors continue to
diagnose females with "Conversion Disorder," rather than taking the time to
properly diagnose their patient. Contact Lloyd W. Phillips for further information or recovery
protocol information:
Note: The
average patient presenting with this syndrome has seen approximately 30+
doctors, is told that she has a "Conversion Disorder" (it's all in her mind), is
typically between 11 and 22 years of age, has received the HPV or other vaccine, and frequently appears to be in good health.
MMR vaccine pushes autism rate to 1 in 38
The CDC proudly announced in 2007 that South Korea was free of measles,
because of the MMR vaccine.
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5613a3.htm
In 2011, 1 in 38 South Korean children now have
autism
In South Korea, A “Japanese Encephalitis” booster vaccine
is given just 4 weeks after the first shot, and, like Gardasil, but then is also
given once each year until age 15. Like the HPV vaccine, it has a history of
causing adverse effects which INTERCELL, and its partner, MERCK, say are not
caused by their vaccine, and go on to say that this is “the wave of the future”
(http://www.medscape.com/viewarticle/414689_7
).
Clinical trials on another MERCK – INTERCELL joint
venture, a Staphylococcus aureus Vaccine called V710, was halted because it was
too obvious that the vaccine was causing multiple organ failure and death,
instead of the usual vaccine collateral damage: autism, paralysis, SIDS, plus
deaths that can more easily be covered up (http://www.intercell.com/main/forbeginners/news/news-full/article/merck-and-intercell-ag-announce-termination-of-phase-iiiii-clinical-trial-of-investigational-staphy/
).
http://www.betterhealthguy.com/joomla/blog/243-dr-stephen-fry-on-fl1953
(http://www.ctv.ca/CTVNews/Health/20110509/south-korea-autism-prevalence-rate-study-110509/
).
An acquaintence, Dr. Stephen Fry (
http://FryLabs.com/ ) has discovered a common protozoan found in people
presenting with MS, CFS, autism, and more, but this protozoan keeps them
from improving. He has temporary called this "FL1953" and has researched
this for the past 10 years, and it loves the ARGENINE found in GLUTEN, and
fats found in the blood. FL1953 can be delivered to your child by the bite
of a flea, mosquito, tick, spider, etc.
See More
By Julie Bailey Obradovic:
"Imagine you are the victim of a violent crime. You don't remember it happening, but you are left with permanent, life-altering damage.
Your parents were eye witnesses. Your friends and extended family members were too. They all positively identified the perpetrator. They are willing to go under oath to testify to what they saw. You go to the police. They reluctantly investigate, but low and behold, they find the finger prints and DNA on the weapon and all over the crime scene. Your wounds match the weapon precisely. You hire a private investigator who finds the same things. The case is a no brainer. You are not worried.
But then, something strange happens. The police give the investigation over to the accused. They start interpreting the evidence their own way. Slowly, they are being exonerated. You object. They don't care.
The case goes to trial. At the trial, the judge dismisses all of the eye witness testimony as irrelevant. He dismisses the evidence from your doctor. He dismisses the original police findings. He dismisses your private investigator. All that he uses to decide the guilt or innocence of the accused is the accused's version of events. They walk free.
The judge tells you and your family you are pathetic, desperate, money-grubbing low-lifes who are immoral and dangerous. They warn you not scare others. The police and the accused go after your private investigator. They go after your doctor. They go after your reputation. They tell everyone they are the victim, not you. You continue on anyway.
In your quest for justice, you discover there are thousands and thousands of people just like you with the exact same story. You discover the police, the judge and the perpetrator are all best friends. You discover the evidence has been tampered with, destroyed, or lost. You discover some victims, whose evidence was so damning and so over the top, secretly got compensated but had to agree to never speak of it again if they wanted their money.
You have nowhere left to go. All you have left is the truth and your voice to warn others, but doubt has been planted. People who have known you and your family your whole life wonder if you've lost your mind. They wonder what the truth is anymore. Congratulations. You now understand the Autism controversy perfectly."
What are the legal implications for administering a vaccine containing aluminum hydroxide?
Based on the preceding science based information and authoritative citations accepted and published at the NIH, the agent (doctor, nurse, etc.) who administers a vaccine(s) containing aluminum hydroxide, appears to be committing possible aggravated (criminal) battery, especially in light of peer reviewed and published evidence stating that aluminum hydroxide causes damage to the brain and other organs, cited from the U.S. Government's own National Institute of Health. The application of (criminal) negligence statutes might also apply if the vaccine administrator fails to test the recipient to determine the effect of the vaccine on the immune system of each individual patient, analogous to testing to determine if a person should receive a driver's license. In light of PFIZER Pharmaceuticals buying and hiding the PMED vaccination device that uses 1/1000th of the antigen found in an intramuscular vaccine, this appears to be a concerted effort (racketeering) to hide an immunization method that would be much safer, and which may not contribute significantly to autism.
OMG! What would
happen if we couldn't get all our vaccinations,
and only got a dozen, like in JAPAN, DENMARK, NORWAY, SWEDEN, or ICELAND????
| Vaccines 2009 Autism 2011 |
Vaccinations before age 5 2009 |
Deaths per 1000 under 5 yrs old, 2009 | Autism Rate in 2011 | Lifespan
Ranking 2009 |
Lifespan
Ranking 2011 |
| Iceland | 11 | 3.9 | 1 in 1,1000 | 1 | 3 |
| Sweden | 11 | 4.0 | 1 in 862 | 2 | 8 |
| Japan | 11 | 4.2 | 1 in 475 | 4 | 1 |
| Norway | 13 | 4.4 | 1 in 2,000 | 5 | 13 |
| Denmark | 12 | 5.8 | 1 in 2,200 | 18 | 36 |
| United States | 36 | 7.8 | 1 in 91 | 34 | 39 ¯ |
| South Korea | 36 | n/a | 1 in 38 | - | - |
We'd all be HEALTHIER and LIVE LONGER !
- and -
There would be less Autism !